REG Publications

Original Research:

REG is committed to publishing all studies that it conducts. All study protocols have been registered and abstracts have been submitted and presented at appropriate respiratory conferences (ERS, ATS, AAAAI, EAACI, IPCRG, APSR and more). A number of the REG-initiated studies are now complete and associated research papers are either in development or have been submitted for publication.

 

Year Publication Title Publication Authors and Reference Online Link
2024 The Interstitial Lung Disease Patient Pathway: From Referral to Diagnosis Graham Lough, Rayid Abdulqawi, Gina Amanda, Katerina Antoniou, Arata Azuma, Milind Baldi, Ahmed Bayoumy, Jürgen Behr, Elisabeth Bendstrup, Demosthenes Bouros, Kevin Brown, Nazia Chaudhuri, Tamera J. Corte, Vincent Cottin, Bruno Crestani, Kevin R. Flaherty, Ian Glaspole, Leticia Kawano-Dourado, Michael P. Keane, Martin Kolb, Fernando J. Martinez, Maria Molina-Molina, Iñigo Ojanguren, Laurence Pearmain, Ganesh Raghu, Paola Rottoli, Stefan C. Stanel, Gabriela Tabaj, Carlo Vancheri, Brenda Varela, Bonnie Wang, Athol Wells, Pilar Rivera-Ortega

https://openres.ersjournals.com/content/early/2024/09/19/23120541.00899-2024
2024 Patient and provider perspectives driving inhaler choice: optimizing sustainable healthcare Graham Lough, Sinthia Bosnic-Anticevich, Nicolas Roche, Omar S. Usmani

CHEST6314, 2024

https://doi.org/10.1016/j.chest.2024.06.3774
2024 Recommendations for asthma monitoring in children: A PeARL
document endorsed by APAPARI, EAACI, INTERASMA, REG,
and WAO
Nikolaos G. Papadopoulos, Adnan Custovic, Antoine Deschildre, James E. Gern, Antonio Nieto Garcia, Michael Miligkos, Wanda Phipatanakul, Gary Wong, Paraskevi Xepapadaki, Ioana Agache, Stefania Arasi, Zeinab Awad El-Sayed, Leonard B. Bacharier, Matteo Bonini, Fulvio Braido, Davide Caimmi, Jose A. Castro-Rodriguez, Zhimin Chen, Michael Clausen, Timothy Craig, Zuzana Diamant, Francine M. Ducharme, Motohiro Ebisawa, Philippe Eigenmann, Wojciech Feleszko, Vincezo Fierro, Alessandro Fiocchi, Luis Garcia-Marcos, Anne Goh, René Maximiliano Gómez, Maia Gotua, Eckard Hamelmann, Gunilla Hedlin, Elham M. Hossny, Zhanat Ispayeva, Daniel J. Jackson, Tuomas Jartti, Miloš Jeseňák, Omer Kalayci, Alan Kaplan, Jon R. Konradsen, Piotr Kuna, Susanne Lau, Peter Le Souef, Robert F. Lemanske, Michael Levin, Mika J. Makela, Alexander G. Mathioudakis, Oleksandr Mazulov, Mário Morais-Almeida, Clare Murray, Karthik Nagaraju, Zoltan Novak, Ruby Pawankar, Marielle W. Pijnenburg, Helena Pite, Paulo M. Pitrez, Petr Pohunek, David Price, Alfred Priftanji, Valeria Ramiconi, Daniela Rivero Yeverino, Graham Roberts, Aziz Sheikh, Kun-Ling Shen, Zsolt Szepfalusi,Ioanna Tsiligianni, Mirjana Turkalj, Steve Turner, Tetiana Umanets, Arunas Valiulis, Susanne Vijveberg, Jiu-Yao Wang, Tonya Winders, Dong Keon Yon, Osman M. Yusuf, Heather J. Zar, WAO Pediatric Asthma Committee

Pediatr Allergy Immunol. 2024;35:e14129

https://doi.org/10.1111/pai.14129
2023 Role of virtual multidisciplinary team meetings in the post-COVID era: a global survey to evaluate the ILD diagnostic pathway https://erj.ersjournals.com/content/62/suppl_67/PA3921
2023

Next generation health guidelines: The role of real-life data in evidence-based medicine

G. Walter Canonica, Ioana Agache, Holger J. Schünemann, Nicolas Roche, David Price, Stefano del Giacco

Allergy 2023 Sep 7. doi: 10.1111/all.15887

https://onlinelibrary.wiley.com/doi/epdf/10.1111/all.15887
2023 Current and Optimal Practices in Childhood Asthma Monitoring
Among Multiple International Stakeholders
Nikolaos G. Papadopoulos, MD, PhD; Alexander G. Mathioudakis, MD, PhD; Adnan Custovic, MSc, DM, MD, PhD; Antoine Deschildre, MD;
Wanda Phipatanakul, MD, MS; Gary Wong, MD; Paraskevi Xepapadaki, MD, PhD; for the PeARL Think Tank
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2804856
2022 Systemic corticosteroids in asthma: A call to action from World Allergy Organization and Respiratory Effectiveness Group
Eugene R. Bleecker, Mona Al-Ahmad, Leif Bjermer, Marco Caminati, Giorgio Walter Canonica, Alan Kaplan, Nikolaos G. Papadopoulos, Nicolas Roche, Dermot Ryan, Yuji Tohda, Anahí Yáñez, David Price
World Allergy Organization Journal Volume 15, Issue 12, 100726, December 01, 2022
https://doi.org/10.1016/j.waojou.2022.100726
2022 Abstracts from the 2021 Respiratory Effectiveness Group Summit
Abstracts from the 6th Respiratory Effectiveness Group Summit, 18 - 20 March 2021.

Respiratory Research, Volume 22, Supp. 1

https://respiratory-research.biomedcentral.com/articles/supplements/volume-22-supplement-1 
2021 Towards Optimum Reporting of Pulmonary Effectiveness Databases and Outcomes (TORPEDO): identifying a core dataset for asthma and COPD studies Job FM van Boven, Sarah J Lucas, Gary Parker, Alan Kaplan, Antigona Trofor, Billie Bonevski, Bruce J Kirenga, Dermot Ryan, Emilio Pizzichini, Eric van Ganse, Erick Wan-Chun Huang, Evelyn Brakema, Gillian Gould, Janwillem Kocks, Jennifer Alison, Jennifer K Quint, Joan B Soriano, John Hurst, Kamran Siddiqi, Katherine Boydell, Marc Miravitlles, Mario Alberto Flores-Valdez, Marise Kasteleyn, Mark FitzGerald, Melanie Boeckmann, Michael Chaiton, Miguel Roman Rodriguez, Muralidhar Kulkarni, Nicolas Roche, Niels Chavannes, Nikolaos G Papadopoulos, Panagiotis Behrakis, Sarah Dennis, Shalini Bassi, Siân Williams, Toby M Maher, Trishul Siddharthan, Veena Kamath, Katia MC Verhamme                               medrxiv.org October 22, 2021 https://doi.org/10.1101/2021.10.14.21264843
2021 Management of asthma in childhood: study protocol of a systematic evidence update by the Paediatric Asthma in Real Life (PeARL) Think Tank
Alexander G Mathioudakis, Michael Miligkos, Cristina Boccabella, Gioulinta S Alimani, Adnan Custovic, A Deschildre, Francine Monique Ducharme, Omer Kalayci, Clare Murray, Antonio Nieto Garcia, Wanda Phipatanakul, David Price, Aziz Sheikh, Ioana Octavia Agache, Leonard Bacharier, Apostolos Beloukas, Andrew Bentley, Matteo Bonini, Jose A Castro-Rodriguez, Giuseppe De Carlo, Timothy Craig, Zuzana Diamant, Wojciech Feleszko, Tim Felton, James E Gern, Jonathan Grigg, Gunilla Hedlin, Elham M Hossny, Despo Ierodiakonou, Tuomas Jartti, Alan Kaplan, Robert F Lemanske, Peter N Le Souëf, Mika J Mäkelä, Georgios A Mathioudakis, Paolo Matricardi, Marina Mitrogiorgou, Mario Morais-Almeida, Karthik Nagaraju, Effie Papageorgiou, Helena Pité, Paulo M C Pitrez, Petr Pohunek, Graham Roberts, Ioanna Tsiligianni, Stephen Turner, Susanne Vijverberg, Tonya A Winders, Gary WK Wong, Paraskevi Xepapadaki, Heather J Zar, Nikolaos G Papadopoulos. BMJ Open, Volume 11, Issue 7 https://bmjopen.bmj.com/content/11/7/e048338
2021 Childhood asthma outcomes during the COVID-19 pandemic: Findings from the PeARL multi-national cohort Nikolaos G Papadopoulos, Alexander G Mathioudakis, Adnan Custovic, Antoine Deschildre, Wanda Phipatanakul, Gary Wong, Paraskevi Xepapadaki, Rola Abou-Taam, Ioana Agache, Jose A Castro-Rodriguez, Zhimin Chen, Pierrick Cros, Jean-Christophe Dubus, Zeinab Awad El-Sayed, Rasha El-Owaidy, Wojciech Feleszko, Vincenzo Fierro, Alessandro Fiocchi, Luis Garcia-Marcos, Anne Goh, Elham M Hossny, Yunuen R Huerta Villalobos, Tuomas Jartti, Pascal Le Roux, Julia Levina, Aida Inés López García, Ángel Mazón Ramos, Mário Morais-Almeida, Clare Murray, Karthik Nagaraju, Major K Nagaraju, Elsy Maureen Navarrete Rodriguez, Leyla Namazova-Baranova, Antonio Nieto Garcia, Cesar Fireth Pozo Beltrán, Thanaporn Ratchataswan, Daniela Rivero Yeverino, Eréndira Rodríguez Zagal , Cyril E Schweitzer, Marleena Tulkki, Katarzyna Wasilczuk, Dan Xu, PeARL collaborators; PeARL Think Tank Allergy 2021 Feb 20 https://onlinelibrary.wiley.com/doi/10.1111/all.14787
2021 A real-life comparative effectiveness study into the addition of antibiotics to the management of asthma exacerbations in primary care https://erj.ersjournals.com/content/early/2020/12/10/13993003.03599-2020
2021 Withdrawal of inhaled corticosteroids versus continuation of triple therapy in patients with COPD in real life: observational comparative effectiveness study Magnussen, H., Lucas, S., Lapperre, T. Quint J.K., Dandurand R.J., Roche N., Papi A., Price D., Miravitlles M. on behalf of the Respiratory Effectiveness Group. Respir Res 22, 25 (2021).

 

https://doi.org/10.1186/s12931-021-01615-0
2020

GINA 2020: Potential Impacts, Opportunities and Challenges for Primary Care

Alan Kaplan, Job F.M.van Boven, Dermot Ryan, Ioanna Tsiligianni, Sinthia Bosnic-Anticevich, on behalf of the REG Adherence Working Group. The Journal of Allergy and Clinical Immunology: In Practice: Volume 9, Issue 4, April 2021, Pages 1516-1519 GINA 2020: Potential Impacts, Opportunities and Challenges for Primary Care - ScienceDirect
2020 Face masks, respiratory patients and COVID-19
Soriano JB, Anzueto A, Bosnic Anticevich S, et al. Face masks, respiratory patients and COVID-19. Eur Respir J 2020 https://erj.ersjournals.com/content/early/2020/09/09/13993003.03325-2020
2020 Changes in Control Status of COPD Over Time and Their Consequences: A Prospective International Study Miravitlles M, Sliwinski P, Rhee CK, Costello, RW, Carter V, Tang JHY, Lapperre TS, Alcazar B, Gouder C, Esquinas C, García-Rivero JL, Kemppinen A, Tee A, Roman-Rodríguez M, Soler-Cataluña JJ and Price DB on behalf of the Respiratory Effectiveness Group (REG). Archives of Bronchopneumology. 21 July (2020). https://doi.org/10.1016/j.arbres.2020.06.003

 

2020 Impact of COVID-19 on pediatric asthma: practice adjustments and disease burden
Nikolaos G Papadopoulos, Adnan Custovic, Antoine Deschildre, Alexander G Mathioudakis, Wanda Phipatanakul, Gary Wong, Paraskevi Xepapadaki, Ioana Agache, Leonard Bacharier, Matteo Bonini, Jose A Castro-Rodriguez, Zhimin Chen, Timothy Craig, Francine M Ducharme, Zeinab Awad El-Sayed, Wojciech Feleszko, Alessandro Fiocchi, Luis Garcia-Marcos, James E Gern, Anne Goh, René Maximiliano Gómez, Eckard H Hamelmann, Gunilla Hedlin, Elham M Hossny, Tuomas Jartti, Omer Kalayci, Alan Kaplan, Jon Konradsen, Piotr Kuna, Susanne Lau, Peter Le Souef, Robert F Lemanske, Mika J Mäkelä, Mário Morais-Almeida, Clare Murray, Karthik Nagaraju, Leyla Namazova-Baranova, Antonio Nieto Garcia, Osman M Yusuf, Paulo M C Pitrez, Petr Pohunek, Cesar Fireth Pozo Beltrán, Graham C Roberts, Arunas Valiulis, Heather J Zar, Pediatric Asthma in Real Life Collaborators

J Allergy Clin Immunol Pract . 2020 Sep;8(8):2592-2599.e3. doi: 10.1016/j.jaip.2020.06.001. Epub 2020 Jun 17

https://pubmed.ncbi.nlm.nih.gov/32561497/
2020 Predictive value of control of COPD for risk of exacerbations: An international, prospective study Miravitlles M, Sliwinski P, Rhee CK, Costello RW, Carter V, Tan JHY, Lapperre TS, Alcazar B, Gouder C, Esquinas C, García-Rivero JL, Kemppinen A, Tee A, Roman-Rodríguez M, Soler-Cataluña JJ, Price DB, Respiratory Effectiveness Group (REG). Respirology. Apr 6 (2020) https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13811

 

2020

Research Priorities in Pediatric Asthma: Results of a Global Survey of Multiple Stakeholder Groups by the Pediatric Asthma in Real Life (PeARL) Think Tank

Alexander G. Mathioudakis, Adnan Custovic, Antoine Deschildre, Francine M. Ducharme, Omer Kalayci, Clare Murray, Antonio Nieto Garcia, Wanda Phipatanakul, David Price, Aziz Sheikh, Ioana Agache, Leonard Bacharier , Matteo Bonini , Jose A. Castro-Rodriguez, Giuseppe De Carlo, Timothy Craig , Zuzana Diamant, Wojciech Feleszko , Despo Ierodiakonou, James E Gern, Jonathan Grigg , Gunilla Hedlin, Elham M. Hossny, Tuomas Jartti, Alan Kaplan, Robert F. Lemanske, Peter Le Souef, Mika J Makela, Paolo M. Matricardi, Michael Miligkos, Mário Morais-Almeida , Helena Pite, Paulo MC Pitrez MD, Petr Pohunek , Graham C. Roberts, Sylvia Sanchez-Garcia, Ioanna Tsiligianni , Steve Turner , Tonya A. Winders, Gary Wong , Paraskevi Xepapadaki, Heather J. Zar, Nikolaos G. Papadopoulos.

The Journal of Allergy and Clinical Immunology: In Practice Volume 8, Issue 6, June 2020, Pages 1953-1960.e9

https://www.sciencedirect.com/science/article/abs/pii/S2213219820301471?dgcid=author
2020 Opportunities to diagnose fibrotic lung diseases in routine care: A primary care cohort study Jones MG, Hillyar CRT, Nibber A, Chisholm A, Wilson A, Maher TMM, Kaplan A, Price D, Walsh S, Richeldi L (2020). Respirology. 2020;10.1111/resp.13836. https://onlinelibrary.wiley.com/doi/full/10.1111/resp.13836
2020 The evolving algorithm of biological selection in severe asthma Nikolaos G. Papadopoulos, Peter Barnes, Giorgio Walter Canonica, Mina Gaga, Liam Heaney, Andrew Menzies‐Gow, Vicky Kritikos, Mark Fitzgerald “The evolving algorithm of biological selection in severe asthma”  Allergy. 2020;75:1555-1563 https://onlinelibrary.wiley.com/doi/full/10.1111/all.14256
2019 Point‐of‐care biomarkers in asthma management: time to move forward Alving, K., Diamant, Z., Lucas, S., Magnussen, H., Pavord, I. D., Piancentini, G. Price, D., Roche, N., Sastre, J., Thomas, M., Usmani, O., Bjermer, L., Respiratory Effectiveness Group, Biomarkers Working Group. (2019) 'Point‐of‐care biomarkers in asthma management: time to move forward', Allergy, 75(4):995-997 https://onlinelibrary.wiley.com/doi/abs/10.1111/all.14045
2019 The relationship between real-world inhaled corticosteroids adherence and asthma outcomes: a multilevel approach Vervloet, M., van Dijk, L., Spreeuwenberg, P., Price, D., Chisholm, A., Van Ganse, E., Pinnock, H., Rand, C. S., Eakin, M. N., Schermer, T., Souverein, P. C., Dima, A. L., Respiratory Effectiveness Group’s Adherence Working Group. (2019) 'The relationship between real-world inhaled corticosteroids adherence and asthma outcomes: a multilevel approach', J Allergy Clin Immunol Pract. Volume 8, Issue 2, February 2020, Pages 626-634 https://www.sciencedirect.com/science/article/abs/pii/S2213219819307809?via%3Dihub
2019 The importance of real-life research in respiratory medicine: manifesto of the Respiratory Effectiveness Group: Endorsed by the International Primary Care Respiratory Group and the World Allergy Organization Roche, N., Anzueto, A., Bosnic Anticevich, S., Kaplan, A., Miravitlles, M., Ryan, D., Soriano, J. B., Usmani, O., Papadopoulos, N. G., Canonica, G. W., Respiratory Effectiveness Group Collaborators. (2019) 'The importance of real-life research in respiratory medicine: manifesto of the Respiratory Effectiveness Group: Endorsed by the International Primary Care Respiratory Group and the World Allergy Organization', Eur Respir J, 54 (3). https://erj.ersjournals.com/content/54/3/1901511.long
2019 Management Of Community-Acquired Pneumonia: An Observational Study In UK Primary Care Launders, N., Ryan, D., Winchester, C.C., Skinner, D., Konduru, P. R., Price, D. B. (2019) 'Management Of Community-Acquired Pneumonia: An Observational Study In UK Primary Care', Prag Obs Res, 10, 53-65. https://www.dovepress.com/management-of-community-acquired-pneumonia-an-observational-study-in-u-peer-reviewed-article-POR
2019 Prevalence and Characteristics of Asthma-COPD Overlap in Routine Primary Care Practices Krishnan, J. A., Nibber, A., Chisholm, A., Price, D., Bateman, E. D., Bjermer, L., van Boven, J. F., Brusselle, G., Costello, R. W., Dandurand, R. J., Diamant, Z., Van Ganse, E., Gouder, C., van Kampen, S. C., Kaplan, A., Kocks, J., Miravitlles, M., Niimi, A., Pizzichini, E., Rhee, C. K., Soriano, J. B., Vogelmeier, C., Román-Rodriguez, M., Carter, V. and Roche, N. (2019) 'Prevalence and Characteristics of Asthma-COPD Overlap in Routine Primary Care Practices', Ann Am Thorac Soc, 16(9). https://www.atsjournals.org/doi/abs/10.1513/AnnalsATS.201809-607OC
2019 The characterisation of interstitial lung disease multidisciplinary team meetings: a global study Richeldi, L., Launders, N., Martinez, F., Walsh, S. L. F., Myers, J., Wang, B., Jones, M., Chisholm, A. and Flaherty, K. R. (2019) 'The characterisation of interstitial lung disease multidisciplinary team meetings: a global study', ERJ Open Res, 5(2). https://openres.ersjournals.com/content/5/2/00209-2018
2019 Quality standards in respiratory real-life effectiveness research: the REal Life EVidence AssessmeNt Tool (RELEVANT): report from the Respiratory Effectiveness Group-European Academy of Allergy and Clinical Immunology Task Force Roche, N., Campbell, J. D., Krishnan, J. A., Brusselle, G., Chisholm, A., Bjermer, L., Thomas, M., van Ganse, E., van den Berge, M., Christoff, G., Quint, J., Papadopoulos, N. G. and Price, D. (2019) 'Quality standards in respiratory real-life effectiveness research: the REal Life EVidence AssessmeNt Tool (RELEVANT): report from the Respiratory Effectiveness Group-European Academy of Allergy and Clinical Immunology Task Force', Clin Transl Allergy, 9, pp. 20. https://ctajournal.biomedcentral.com/articles/10.1186/s13601-019-0255-x
2019 The REal Life EVidence AssessmeNt Tool (RELEVANT): development of a novel quality assurance asset to rate observational comparative effectiveness research studies Campbell, J. D., Perry, R., Papadopoulos, N. G., Krishnan, J., Brusselle, G., Chisholm, A., Bjermer, L., Thomas, M., van Ganse, E., van den Berge, M., Quint, J., Price, D. and Roche, N. (2019) 'The REal Life EVidence AssessmeNt Tool (RELEVANT): development of a novel quality assurance asset to rate observational comparative effectiveness research studies', Clin Transl Allergy, 9, pp. 21. https://ctajournal.biomedcentral.com/articles/10.1186/s13601-019-0256-9
2018 Matched cohort study of therapeutic strategies to prevent preschool wheezing/asthma attacks Grigg J, Nibber A, Paton JY, Chisholm A, Guilbert TW, Kaplan A, Turner S, Roche N, Hillyer EV, Price DB. (2018) 'Matched cohort study of therapeutic strategies to prevent preschool wheezing/asthma attacks', J Asthma Allergy, 11. https://www.dovepress.com/matched-cohort-study-of-therapeutic-strategies-to-prevent-preschool-wh-peer-reviewed-fulltext-article-JAA
2018 Abstracts from the 2018 Respiratory Effectiveness Group Summit Respiratory Effectiveness Group (2018) 'Abstracts from the 2018 Respiratory Effectiveness Group Summit', Respiratory Research, 19 (S1) https://respiratory-research.biomedcentral.com/articles/supplements/volume-19-supplement-1
2018 Amoxicillin is associated with a lower risk of further antibiotic prescriptions for lower respiratory tract infections in primary care – A database analysis spanning over 30 years Stolbrink, M., Bonnett, L. J. and Blakey, J. D. (2018) 'Amoxicillin is associated with a lower risk of further antibiotic prescriptions for lower respiratory tract infections in primary care – A database analysis spanning over 30 years', Eur Clin Respir K, 5(1). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201792/
2018 Antibiotic choice and duration associate with repeat prescriptions in infective asthma exacerbations Stolbrink, M., Bonnett, L. J. and Blakey, J. D. (2018) 'Antibiotic choice and duration associate with repeat prescriptions in infective asthma exacerbations', J Allergy Clin Immunol Pract. https://www.jaci-inpractice.org/article/S2213-2198(18)30530-0/abstract
2018 Performance of database-derived severe exacerbations and asthma control measures in asthma: responsiveness and predictive utility in a UK primary care database with linked questionnaire data Colice, G., Chisholm, A., Dima, A. L., Reddel, H. K., Burden, A., Martin, R. J., Brusselle, G., Popov, T. A., von Ziegenweidt, J. and Price, D. B. (2018) 'Performance of database-derived severe exacerbations and asthma control measures in asthma: responsiveness and predictive utility in a UK primary care database with linked questionnaire data', Pragmat Obs Res, 9, pp. 29-42 https://www.dovepress.com/performance-of-database-derived-severe-exacerbations-and-asthma-contro-peer-reviewed-article-POR
2018 Applying UK real-world primary care data to predict asthma attacks in 3776 well-characterised children: a retrospective cohort study Turner, S. W., Murray, C., Thomas, M., Burden, A. and Price, D. B. (2018) 'Applying UK real-world primary care data to predict asthma attacks in 3776 well-characterised children: a retrospective cohort study', NPJ Prim Care Respir Med, 28(1), pp. 28. https://www.nature.com/articles/s41533-018-0095-5.pdf?origin=ppub
2018 Harmonizing the Nomenclature for Therapeutic Aerosol Particle Size: A Proposal Hillyer, E. V., Price, D. B., Chrystyn, H., Martin, R. J., Israel, E., van Aalderen, W. M. C., Papi, A., Usmani, O. S. and Roche, N. (2018) 'Harmonizing the Nomenclature for Therapeutic Aerosol Particle Size: A Proposal', J Aerosol Med Pulm Drug Deliv, 31(2), pp. 111-113. https://www.liebertpub.com/doi/10.1089/jamp.2017.1396
2018 Extrafine Versus Fine Inhaled Corticosteroids in Relation to Asthma Control: A Systematic Review and Meta-Analysis of Observational Real-Life Studies Sonnappa, S., McQueen, B., Postma, D. S., Martin, R. J., Roche, N., Grigg, J., Guilbert, T., Gouder, C., Pizzichini, E., Niimi, A., Phipatanakul, W., Chisholm, A., Dandurand, R. J., Kaplan, A., Israel, E., Papi, A., van Aalderen, W. M. C., Usmani, O. S. and Price, D. B. (2018) 'Extrafine Versus Fine Inhaled Corticosteroids in Relation to Asthma Control: A Systematic Review and Meta-Analysis of Observational Real-Life Studies', J Allergy Clin Immunol Pract, 6(3), pp. 907-915.e7. https://www.sciencedirect.com/science/article/pii/S2213219817305573?via%3Dihub
2018 Trends of testing for and diagnosis of alpha-1 antitrypsin deficiency in the UK: more testing is needed Soriano, J. B., Lucas, S. J., Jones, R., Miravitlles, M., Carter, V., Small, I., Price, D., Mahadeva, R. and Group', R. E. (2018) 'Trends of testing for and diagnosis of alpha-1 antitrypsin deficiency in the UK: more testing is needed', Eur Respir J. http://erj.ersjournals.com/content/early/2018/05/10/13993003.00360-2018
2018 Evaluation of criteria for clinical control in a prospective, international, multicenter study of patients with COPD Miravitlles, M., Sliwinski, P., Rhee, C. K., Costello, R. W., Carter, V., Tan, J., Lapperre, T. S., Alcazar, B., Gouder, C., Esquinas, C., García-Rivero, J. L., Kemppinen, A., Tee, A., Roman-Rodríguez, M., Soler-Cataluña, J. J. and Price, D. B. (2018) 'Evaluation of criteria for clinical control in a prospective, international, multicenter study of patients with COPD', Respir Med, 136, pp. 8-14 https://www.resmedjournal.com/article/S0954-6111(18)30028-3/fulltext
2017 The cost of systemic corticosteroid-induced morbidity in severe asthma: a health economic analysis Barry, L. E., Sweeney, J., O'Neill, C., Price, D. and Heaney, L. G. (2017) 'The cost of systemic corticosteroid-induced morbidity in severe asthma: a health economic analysis', Respir Res, 18(1), pp. 129. https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-017-0614-x
2017 Identifying Risk of Future Asthma Attacks Using UK Medical Record Data: A Respiratory Effectiveness Group Initiative Blakey, J. D., Price, D. B., Pizzichini, E., Popov, T. A., Dimitrov, B. D., Postma, D. S., Josephs, L. K., Kaplan, A., Papi, A., Kerkhof, M., Hillyer, E. V., Chisholm, A. and Thomas, M. (2017) 'Identifying Risk of Future Asthma Attacks Using UK Medical Record Data: A Respiratory Effectiveness Group Initiative', J Allergy Clin Immunol Pract, 5(4), pp. 1015-1024.e8. https://www.jaci-inpractice.org/article/S2213-2198(16)30564-5/abstract
2017 Abstracts from the 2017 Respiratory Effectiveness Group Summit: what lies ahead? Translating the value and potential of real-life evidence Canonica, W. G., Usmani, O. S., Eid, N. S., Soriano, J. B., Bouros, D., Christoff, G., Roche, N. and Navarrete, B. A. (2017) 'Abstracts from the 2017 Respiratory Effectiveness Group Summit: what lies ahead? Translating the value and potential of real-life evidence', npj Primary Care Respiratory Medicine, 27. http://images.nature.com/full/nature-assets/npjpcrm/abstracts/npjpcrm20179.pdf
2017 Personalising care of adults with asthma from Asia: a modified e-Dephi consensus study to inform management tailored to attitude and control profiles Chisholm, A., Price, D. B., Pinnock, H., Lee, T. T., Roa, C., Cho, S. H., David-Wang, A., Wong, G., van der Molen, T., Ryan, D., Castillo-Carandang, N. and Yong, Y. V. (2017) 'Personalising care of adults with asthma from Asia: a modified e-Dephi consensus study to inform management tailored to attitude and control profiles', NPJ Prim Care Respir Med, 27, pp. 16089. https://www.nature.com/articles/npjpcrm201689
2017 Effective deployment of technology-supported management of chronic respiratory conditions: a call for stakeholder engagement Costello, R. W., Dima, A. L., Ryan, D., McIvor, R. A., Boycott, K., Chisholm, A., Price, D. and Blakey, J. D. (2017) 'Effective deployment of technology-supported management of chronic respiratory conditions: a call for stakeholder engagement', Pragmat Obs Res, 8, pp. 119-128. https://www.dovepress.com/effective-deployment-of-technology-supported-management-of-chronic-res-peer-reviewed-article-POR
2017 Cardiovascular risks in smokers treated with nicotine replacement therapy: a historical cohort study Dollerup, J., Vestbo, J., Murray-Thomas, T., Kaplan, A., Martin, R. J., Pizzichini, E., Pizzichini, M. M. M., Burden, A., Martin, J. and Price, D. B. (2017) 'Cardiovascular risks in smokers treated with nicotine replacement therapy: a historical cohort study', Clin Epidemiol, 9, pp. 231-243. https://www.dovepress.com/cardiovascular-risks-in-smokers-treated-with-nicotine-replacement-ther-peer-reviewed-article-CLEP
2017 Comparative effectiveness of therapies for preschool children with recurrent wheezing Grigg, J., Nibber, A., Hillyer, E., Chisholm, A. and Price, D. (2017) 'Comparative effectiveness of therapies for preschool children with recurrent wheezing', European Respiratory Journal,50(Suppl 61), pp. PA588. http://erj.ersjournals.com/content/50/suppl_61/PA588
2017 Blood eosinophil count and exacerbation risk in patients with COPD Kerkhof, M., Sonnappa, S., Postma, D. S., Brusselle, G., Agustí, A., Anzueto, A., Jones, R., Papi, A., Pavord, I., Pizzichini, E., Popov, T., Roche, N., Ryan, D., Thomas, M., Vogelmeier, C., Chisholm, A., Freeman, D., Bafadhel, M., Hillyer, E. V. and Price, D. B. (2017) 'Blood eosinophil count and exacerbation risk in patients with COPD', Eur Respir J, 50(1). http://erj.ersjournals.com/content/50/1/1700761
2017 The diagnosis of idiopathic pulmonary fibrosis: current and future approaches Martinez, F. J., Chisholm, A., Collard, H. R., Flaherty, K. R., Myers, J., Raghu, G., Walsh, S. L., White, E. S. and Richeldi, L. (2017) 'The diagnosis of idiopathic pulmonary fibrosis: current and future approaches', Lancet Respir Med, 5(1), pp. 61-71. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(16)30325-3/fulltext
2017 Comparative Effectiveness of Step-up Therapies in Children with Asthma Prescribed Inhaled Corticosteroids: A Historical Cohort Study Murray, C. S., Thomas, M., Richardson, K., Price, D. B. and Turner, S. W. (2017) 'Comparative Effectiveness of Step-up Therapies in Children with Asthma Prescribed Inhaled Corticosteroids: A Historical Cohort Study', J Allergy Clin Immunol Pract, 5(4), pp. 1082-1090.e7. https://www.jaci-inpractice.org/article/S2213-2198(17)30011-9/abstract
2017 Real-Life Outcomes for Patients with Asthma Prescribed Spacers for Use with Either Extrafine- or Fine-Particle Inhaled Corticosteroids Guilbert, T. W., Colice, G., Grigg, J., van Aalderen, W., Martin, R. J., Israel, E., Postma, D. S., Roche, N., Phipatanakul, W., Hillyer, E. V., Evans, J. M., Dolovich, M. B., Price, D. B. and Group, R. E. (2017) 'Real-Life Outcomes for Patients with Asthma Prescribed Spacers for Use with Either Extrafine- or Fine-Particle Inhaled Corticosteroids', J Allergy Clin Immunol Pract, 5(4), pp. 1040-1049.e4. https://www.sciencedirect.com/science/article/pii/S2213219816305840?via%3Dihub
2017 Validating the Concept of COPD Control: A Real-world Cohort Study from the United Kingdom Nibber, A., Chisholm, A., Soler-Cataluña, J. J., Alcazar, B., Price, D. and Miravitlles, M. (2017) 'Validating the Concept of COPD Control: A Real-world Cohort Study from the United Kingdom', COPD, 14(5), pp. 504-512. https://www.tandfonline.com/doi/abs/10.1080/15412555.2017.1350154?journalCode=icop20
2017 Global characterisation of routine care interstitial lung disease diagnostic practice Richeldi, L., Martinez, F. J., Flaherty, K. R., Walsh, S. L. F., Myers, J., Launders, N. and Chisholm, A. (2017) 'Global characterisation of routine care interstitial lung disease diagnostic practice', European Respiratory Journal, 50(Suppl 61), pp. PA3824. http://erj.ersjournals.com/content/50/suppl_61/PA3824
2017 Use of electronic medical records and biomarkers to manage risk and resource efficiencies Ryan, D., Blakey, J., Chisholm, A., Price, D., Thomas, M., Ställberg, B., Lisspers, K., Kocks, J. W. H. and Group, R. E. (2017) 'Use of electronic medical records and biomarkers to manage risk and resource efficiencies', Eur Clin Respir J, 4(1), pp. 1293386. https://www.tandfonline.com/doi/full/10.1080/20018525.2017.1293386
2017 Risk of pneumonia in obstructive lung disease: A real-life study comparing extra-fine and fine-particle inhaled corticosteroids Sonnappa, S., Martin, R., Israel, E., Postma, D., van Aalderen, W., Burden, A., Usmani, O. S., Price, D. B. and Respiratory Effectiveness Group, S. a. A. S. G. (2017) 'Risk of pneumonia in obstructive lung disease: A real-life study comparing extra-fine and fine-particle inhaled corticosteroids', PLoS One, 12(6), pp. e0178112. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178112
2017 Inhaled Corticosteroid Adherence Patterns in a Longitudinal Asthma Cohort Souverein, P. C., Koster, E. S., Colice, G., van Ganse, E., Chisholm, A., Price, D., Dima, A. L. and Group, R. E. G. s. A. W. (2017) 'Inhaled Corticosteroid Adherence Patterns in a Longitudinal Asthma Cohort', J Allergy Clin Immunol Pract, 5(2), pp. 448-456.e2. https://www.sciencedirect.com/science/article/pii/S2213219816304238?via%3Dihub
2017 Long-Acting β-Agonist in Combination or Separate Inhaler as Step-Up Therapy for Children with Uncontrolled Asthma Receiving Inhaled Corticosteroids Turner, S., Richardson, K., Murray, C., Thomas, M., Hillyer, E. V., Burden, A., Price, D. B. and Group, R. E. (2017) 'Long-Acting β-Agonist in Combination or Separate Inhaler as Step-Up Therapy for Children with Uncontrolled Asthma Receiving Inhaled Corticosteroids', J Allergy Clin Immunol Pract, 5(1), pp. 99-106.e3. https://www.sciencedirect.com/science/article/pii/S221321981630201X?via%3Dihub
2016 Inappropriate asthma therapy-a tale of two countries: a parallel population-based cohort study Belhassen, M., Nibber, A., Van Ganse, E., Ryan, D., Langlois, C., Appiagyei, F., Skinner, D., Laforest, L., Soriano, J. B. and Price, D. (2016) 'Inappropriate asthma therapy-a tale of two countries: a parallel population-based cohort study', NPJ Prim Care Respir Med, 26, pp. 16076. https://www.nature.com/articles/npjpcrm201676
2016 "Trying, But Failing" - The Role of Inhaler Technique and Mode of Delivery in Respiratory Medication Adherence Braido, F., Chrystyn, H., Baiardini, I., Bosnic-Anticevich, S., van der Molen, T., Dandurand, R. J., Chisholm, A., Carter, V., Price, D. and Group, R. E. (2016) '"Trying, But Failing" - The Role of Inhaler Technique and Mode of Delivery in Respiratory Medication Adherence', J Allergy Clin Immunol Pract, 4(5), pp. 823-32. https://www.jaci-inpractice.org/article/S2213-2198(16)30009-5/abstract
2016 2016 Respiratory Effectiveness Group Annual Summit Report-impact & influence of real-world respiratory evidence Chisholm, A., Eid, N., Alcázar-Navarrete, B., Barot, A., Christoff, G. and Price, D. B. (2016) '2016 Respiratory Effectiveness Group Annual Summit Report-impact & influence of real-world respiratory evidence', J Thorac Dis, 8(Suppl 5), pp. S435-44. http://jtd.amegroups.com/article/view/8423/7486
2016 The Seven Stages of Man: The Role of Developmental Stage on Medication Adherence in Respiratory Diseases Costello, R. W., Foster, J. M., Grigg, J., Eakin, M. N., Canonica, W., Yunus, F., Ryan, D. and Group, R. E. (2016) 'The Seven Stages of Man: The Role of Developmental Stage on Medication Adherence in Respiratory Diseases', J Allergy Clin Immunol Pract, 4(5), pp. 813-20. https://www.jaci-inpractice.org/article/S2213-2198(16)30066-6/abstract?code=jaip-site
2016 Mapping the Asthma Care Process: Implications for Research and Practice Dima, A. L., de Bruin, M., Van Ganse, E. and group, A.-L. (2016) 'Mapping the Asthma Care Process: Implications for Research and Practice', J Allergy Clin Immunol Pract, 4(5), pp. 868-76. https://www.jaci-inpractice.org/article/S2213-2198(16)30130-1/abstract?code=jaip-site
2016 Multi-component assessment of chronic obstructive pulmonary disease: an evaluation of the ADO and DOSE indices and the global obstructive lung disease categories in international primary care data sets Jones, R. C., Price, D., Chavannes, N. H., Lee, A. J., Hyland, M. E., Ställberg, B., Lisspers, K., Sundh, J., van der Molen, T., Tsiligianni, I. and IPCRG, U. G. o. t. (2016) 'Multi-component assessment of chronic obstructive pulmonary disease: an evaluation of the ADO and DOSE indices and the global obstructive lung disease categories in international primary care data sets', NPJ Prim Care Respir Med, 26, pp. 16010. https://www.nature.com/articles/npjpcrm201610
2016 Time to get real: critical and imperative change required in evidence evaluation Price, D. B. (2016) 'Time to get real: critical and imperative change required in evidence evaluation', J Thorac Dis, 8(Suppl 5), pp. S431-4. http://jtd.amegroups.com/article/view/8422/7484
2016 Add-on LABA in a separate inhaler as asthma step-up therapy Price, D. B., Colice, G., Israel, E., Roche, N., Postma, D. S., Guilbert, T. W., van Aalderen, W. M., Grigg, J., Hillyer, E. V., Thomas, V. and Martin, R. J. (2016b) 'Add-on LABA in a separate inhaler as asthma step-up therapy', ERJ Open Res, 2(2). http://openres.ersjournals.com/content/2/2/00106-2015
2016 Predicting frequent asthma exacerbations using blood eosinophil count and other patient data routinely available in clinical practice Price, D., Wilson, A. M., Chisholm, A., Rigazio, A., Burden, A., Thomas, M. and King, C. (2016a) 'Predicting frequent asthma exacerbations using blood eosinophil count and other patient data routinely available in clinical practice', J Asthma Allergy, 9, pp. 1-12. https://www.dovepress.com/predicting-frequent-asthma-exacerbations-using-blood-eosinophil-count--peer-reviewed-article-JAA
2016 Comorbidity in severe asthma requiring systemic corticosteroid therapy: cross-sectional data from the Optimum Patient Care Research Database and the British Thoracic Difficult Asthma Registry Sweeney, J., Patterson, C. C., Menzies-Gow, A., Niven, R. M., Mansur, A. H., Bucknall, C., Chaudhuri, R., Price, D., Brightling, C. E., Heaney, L. G. and Network, B. T. S. D. A. (2016) 'Comorbidity in severe asthma requiring systemic corticosteroid therapy: cross-sectional data from the Optimum Patient Care Research Database and the British Thoracic Difficult Asthma Registry', Thorax, 71(4), pp. 339-46. http://thorax.bmj.com/content/71/4/339
2016 Enhancing Respiratory Medication Adherence: The Role of Health Care Professionals and Cost-Effectiveness Considerations van Boven, J. F., Ryan, D., Eakin, M. N., Canonica, G. W., Barot, A., Foster, J. M. and Group, R. E. (2016) 'Enhancing Respiratory Medication Adherence: The Role of Health Care Professionals and Cost-Effectiveness Considerations', J Allergy Clin Immunol Pract, 4(5), pp. 835-46. https://www.jaci-inpractice.org/article/S2213-2198(16)30016-2/abstract?code=jaip-site
2016 Respiratory Medication Adherence: Toward a Common Language and a Shared Vision Van Ganse, E. and Price, D. (2016) 'Respiratory Medication Adherence: Toward a Common Language and a Shared Vision', J Allergy Clin Immunol Pract, 4(5), pp. 799-801. https://www.jaci-inpractice.org/article/S2213-2198(16)30103-9/pdf
2016 What We Mean When We Talk About Adherence in Respiratory Medicine Vrijens, B., Dima, A. L., Van Ganse, E., van Boven, J. F., Eakin, M. N., Foster, J. M., de Bruin, M., Chisholm, A. and Price, D. (2016) 'What We Mean When We Talk About Adherence in Respiratory Medicine', J Allergy Clin Immunol Pract, 4(5), pp. 802-12. https://www.jaci-inpractice.org/article/S2213-2198(16)30158-1/abstract?code=jaip-site
2016 A practical tool for primary care antimicrobial stewardship in children Winchester, C. C., Chisholm, A. and Price, D. (2016) 'A practical tool for primary care antimicrobial stewardship in children', Lancet Respir Med, 4(11), pp. 850-852. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(16)30272-7/fulltext
2015 Initial step-up treatment changes in asthmatic children already prescribed inhaled corticosteroids: a historical cohort study Turner, S. W., Richardson, K., Burden, A., Thomas, M., Murray, C. and Price, D. (2015) 'Initial step-up treatment changes in asthmatic children already prescribed inhaled corticosteroids: a historical cohort study', NPJ Prim Care Respir Med, 25, pp. 15041. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498242/
2015 Predicting frequent COPD exacerbations using primary care data Kerkhof, M., Freeman, D., Jones, R., Chisholm, A., Price, D. B. and Group, R. E. (2015) 'Predicting frequent COPD exacerbations using primary care data', Int J Chron Obstruct Pulmon Dis, 10, pp. 2439-50. https://www.dovepress.com/predicting-frequent-copd-exacerbations-using-primary-care-data-peer-reviewed-article-COPD
2015 Real-world research and its importance in respiratory medicine Price, D., Brusselle, G., Roche, N., Freeman, D. and Chisholm, A. (2015a) 'Real-world research and its importance in respiratory medicine', Breathe (Sheff), 11(1), pp. 26-38. http://breathe.ersjournals.com/content/11/1/26
2015 Differential effects of inhaled corticosteroids in smokers/ex-smokers and nonsmokers with asthma Roche, N., Postma, D. S., Colice, G., Burden, A., Guilbert, T. W., Israel, E., Martin, R. J., van Aalderen, W. M., Grigg, J., Hillyer, E. V., von Ziegenweidt, J. and Price, D. B. (2015) 'Differential effects of inhaled corticosteroids in smokers/ex-smokers and nonsmokers with asthma', Am J Respir Crit Care Med, 191(8), pp. 960-4. https://www.atsjournals.org/doi/10.1164/rccm.201411-2116LE
2015 Small-particle Inhaled Corticosteroid as First-line or Step-up Controller Therapy in Childhood Asthma van Aalderen, W. M., Grigg, J., Guilbert, T. W., Roche, N., Israel, E., Martin, R. J., Colice, G., Postma, D. S., Hillyer, E. V., Burden, A., Thomas, V., von Ziegenweidt, J. and Price, D. (2015) 'Small-particle Inhaled Corticosteroid as First-line or Step-up Controller Therapy in Childhood Asthma', J Allergy Clin Immunol Pract, 3(5), pp. 721-31.e16. https://www.jaci-inpractice.org/article/S2213-2198(15)00240-8/abstract
2014 Integrating patients into meaningful real-world research Bartlett, S. J., Barnes, T. and McIvor, R. A. (2014) 'Integrating patients into meaningful real-world research', Ann Am Thorac Soc, 11 Suppl 2, pp. S112-7. https://www.atsjournals.org/doi/abs/10.1513/AnnalsATS.201309-327RM
2014 The "e" in cost-effectiveness analyses. A case study of omalizumab efficacy and effectiveness for cost-effectiveness analysis evidence Campbell, J. D., McQueen, R. B. and Briggs, A. (2014) 'The "e" in cost-effectiveness analyses. A case study of omalizumab efficacy and effectiveness for cost-effectiveness analysis evidence', Ann Am Thorac Soc, 11 Suppl 2, pp. S105-11. https://www.atsjournals.org/doi/abs/10.1513/AnnalsATS.201309-295RM
2014 The arch conference declaration. Helping to further the science of pragmatic research Martin, R. J., Chisholm, A. M. and Price, D. (2014a) 'The arch conference declaration. Helping to further the science of pragmatic research', Ann Am Thorac Soc, 11 Suppl 2, pp. S83-4. https://www.atsjournals.org/doi/pdf/10.1513/AnnalsATS.201308-256RM
2014 Phase IV implementation studies. The forgotten finale to the complex intervention methodology framework Pinnock, H., Epiphaniou, E. and Taylor, S. J. (2014) 'Phase IV implementation studies. The forgotten finale to the complex intervention methodology framework', Ann Am Thorac Soc, 11 Suppl 2, pp. S118-22. https://www.atsjournals.org/doi/pdf/10.1513/AnnalsATS.201308-259RM
2014 Complementing the randomized controlled trial evidence base. Evolution not revolution Price, D., Bateman, E. D., Chisholm, A., Papadopoulos, N. G., Bosnic-Anticevich, S., Pizzichini, E., Hillyer, E. V. and Buist, A. S. (2014a) 'Complementing the randomized controlled trial evidence base. Evolution not revolution', Ann Am Thorac Soc, 11 Suppl 2, pp. S92-8. https://www.atsjournals.org/doi/abs/10.1513/AnnalsATS.201308-276RM
2014 Integrating evidence for managing asthma in patients who smoke Price, D., Bjermer, L., Popov, T. A. and Chisholm, A. (2014b) 'Integrating evidence for managing asthma in patients who smoke', Allergy Asthma Immunol Res, 6(2), pp. 114-20. https://synapse.koreamed.org/DOIx.php?id=10.4168/aair.2014.6.2.114
2014 Quality standards for real-world research. Focus on observational database studies of comparative effectiveness Roche, N., Reddel, H., Martin, R., Brusselle, G., Papi, A., Thomas, M., Postma, D., Thomas, V., Rand, C., Chisholm, A., Price, D. and Group, R. E. (2014) 'Quality standards for real-world research. Focus on observational database studies of comparative effectiveness', Ann Am Thorac Soc, 11 Suppl 2, pp. S99-104. https://www.atsjournals.org/doi/abs/10.1513/AnnalsATS.201309-300RM
2014 Respiratory guidelines--which real world? Wong, G. W., Miravitlles, M., Chisholm, A., Krishnan, J. A. and Krishnan, J. (2014) 'Respiratory guidelines--which real world?', Ann Am Thorac Soc, 11 Suppl 2, pp. S85-91. https://www.atsjournals.org/doi/abs/10.1513/AnnalsATS.201309-298RM
2013 Feasibility and ethics Price, D., Roche, N., Martin, R., Chisholm, A. and Collaborators, R. E. G. (2013) 'Feasibility and ethics', Am J Respir Crit Care Med, 188(11), pp. 1368-9. https://www.atsjournals.org/doi/full/10.1164/rccm.201307-1250LE
2013 Integrating real-life studies in the global therapeutic research framework Roche, N., Reddel, H. K., Agusti, A., Bateman, E. D., Krishnan, J. A., Martin, R. J., Papi, A., Postma, D., Thomas, M., Brusselle, G., Israel, E., Rand, C., Chisholm, A., Price, D. and Group, R. E. (2013) 'Integrating real-life studies in the global therapeutic research framework', Lancet Respir Med, 1(10), pp. e29-30. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(13)70199-1/fulltext

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